CARE Panel: The Ethics of Human Challenge Studies

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October 23, 2023
12:00PM - 1:15PM
Zoom

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2023-10-23 12:00:00 2023-10-23 13:15:00 CARE Panel: The Ethics of Human Challenge Studies Register Now Human challenge trials, which intentionally expose healthy volunteers to disease, have historically been part of scientific research and have contributed to vital scientific advances in drug and vaccine development. Nevertheless, such research has been criticized as conflicting with the guiding principle in medicine to do no harm. This panel will discuss: under what conditions, if ever, are such trials appropriate? And are there upper limits of risk that we can ask participants to incur for the purposes of research? Featuring Panelists:  Seema K. Shah, JD (Associate Professor of Pediatrics at Northwestern University Medical School & Director of Research Ethics at Lurie Children’s Hospital) Susan L. Koletar, MD, FACP, FIDSA (Professor of Infectious Diseases and Internal Medicine, Director of the Division of Infectious Diseases, and Principal Investigator of AIDS Clinical Trials Unit; OSU) Zoom Center for Ethics and Human Values cehv@osu.edu America/New_York public

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Human challenge trials, which intentionally expose healthy volunteers to disease, have historically been part of scientific research and have contributed to vital scientific advances in drug and vaccine development. Nevertheless, such research has been criticized as conflicting with the guiding principle in medicine to do no harm. This panel will discuss: under what conditions, if ever, are such trials appropriate? And are there upper limits of risk that we can ask participants to incur for the purposes of research?

Featuring Panelists: 

Seema K. Shah, JD (Associate Professor of Pediatrics at Northwestern University Medical School & Director of Research Ethics at Lurie Children’s Hospital)

Susan L. Koletar, MD, FACP, FIDSA (Professor of Infectious Diseases and Internal Medicine, Director of the Division of Infectious Diseases, and Principal Investigator of AIDS Clinical Trials Unit; OSU)

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